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 Free Download Tim Meyer, "Vascular Disruptive Agents for the Treatment of Cancer" English | 2010 | pages: 257 | ISBN: 1441966080, 1489982264 | PDF | 6,3 mb Angiogenesis (formation of new vessels from pre-existing ones) is a crucial early event in the process of tumor development. New vessels supply the tumor with nutrients that are needed for further local growth and enable distant metastases (Folkman 1995). Judah Folkman (1971) highlighted the potential therapeutic imp- cations of tumor angiogenesis. He hypothesized that if tumor angiogenesis is inhibited, then tumor growth and metastasis will be impaired greatly or even impossible. The subsequent quest for endogenous and exogenous inhibitors of angiogenesis has yielded a variety of promising therapeutic agents that block one or more angiogenic pathways, a few of which have been approved by the FDA (e. g. , bevacizumab, sorafenib, sunitinib) for use as single agents or in combination with chemotherapy in specific populations of cancer patients (Sessa et al. 2008). There has also been a dramatic expansion in the exploration of novel anti-angiogenic agents pre-clinically and in clinical trials (Ferrara 2002). Some of the most promising data comes from the development of agents that inhibit one of the key growth factors involved in tumor angiogenesis - vascular endothelial growth factor (VEGF) (Ferrara et al. 2003). Bevacizumab is a monoclonal antibody against VEGF that was the first an- angiogenic agent that improved significantly the overall survival of patients with colorectal and non-squamous non-small cell lung cancer (Ferrara et al. 2005). Various agents that target tumor angiogenesis are currently under investigation in different cancer types in many clinical trials (Ferrara and Kerbel 2005).
 Free Download Disruptive Technologies in International Business: Challenges and Opportunities for Emerging Markets by Alka Maurya, J. Mark Munoz, Loveleen Gaur English | July 24, 2023 | ISBN: 3110738597 | 117 pages | MOBI | 1.81 Mb New technologies such as artificial intelligence, blockchain, the Internet of Things (IoT), etc. are redefining business processes around the world at a rapid rate and resulting in both great opportunities and challenges for businesses. Though these technologies are extensively being used in developed countries, emerging economies are also not far behind.  Free Download Disruptive Information Technologies for a Smart Society English | 2024 | ISBN: 3031507541 | 533 Pages | PDF (True) | 46 MB This book aims at meeting the challenge of getting along with today's unprecedented rate of innovation supported by disruptive digital technologies, which changed the perception of the productivity and effectiveness and opened a gateway to more than ever dynamic advances in solving the important societal challenges.  Free Download Disruptive Thinking – How To See Huge Opportunities Published 1/2024 MP4 | Video: h264, 1920x1080 | Audio: AAC, 44.1 KHz Language: English | Size: 1.47 GB | Duration: 2h 7m Challenge routine approaches and drive innovation
 Free Download Disruptive Technologies for Big Data and Cloud Applications: Proceedings of ICBDCC 2021 by J. Dinesh Peter, Steven Lawrence Fernandes, Amir H. Alavi English | EPUB | 2022 | 880 Pages | ISBN : 9811921768 | 185.7 MB This book provides a written record of the synergy that already exists among the research communities and represents a solid framework in the advancement of big data and cloud computing disciplines from which new interaction will result in the future. This book is a compendium of the International Conference on Big Data and Cloud Computing (ICBDCC 2021). It includes recent advances in big data analytics, cloud computing, the Internet of nano things, cloud security, data analytics in the cloud, smart cities and grids, etc. This book primarily focuses on the application of knowledge that promotes ideas for solving the problems of society through cutting-edge technologies. The articles featured in this book provide novel ideas that contribute to the growth of world-class research and development. The contents of this book are of interest to researchers and professionals alike.  Free Download Karen Bearss, "Parent Training for Disruptive Behavior: The RUBI Autism Network, Parent Workbook " English | ISBN: 0190627840 | 2018 | 112 pages | PDF | 2 MB To access the video vignettes, please visit oup.com/RUBI
 Free Download Disruptive Technologies: A Framework to Understand, Evaluate and Respond to Digital Disruption by Paul Armstrong English | January 31, 2023 | ISBN: 139860920X | 248 pages | MOBI | 1.71 Mb The next two decades will see more waves of technological disruption than the previous fifty. Adaptability and understanding of technological changes are now mission-critical to every business.  Free Download Growth Hacking Techniques, Disruptive Technology by Robert Peters English | 2014 | ISBN: 1910085286 | 166 Pages | EPUB | 572.4 KB Growth hacking marketing strategy - Want to grow from 0 to 1+million customers in a few months? Discover how 40 of today's largest online companies got started.  Free Download Disruptive Emerging Transportation Technologies by Heng Wei, Yinhai Wang English | 2022 | ISBN: 0784415986 | 345 Pages | True PDF | 10 MB  Free Download The Innovator's Guide to Growth: Putting Disruptive Innovation to Work By Scott D. Anthony, Mark W. Johnson, Joseph V. Sinfield, Elizabeth J. Altman 2008 | 320 Pages | ISBN: 1591398460 | EPUB | 2 MB More than a decade ago, Clayton Christensen's breakthrough book The Innovator's Dilemma illustrated how disruptive innovations drive industry transformation and market creation. Christensen's research demonstrated how growth-seeking incumbents must develop the capability to deflect disruptive attacks and seize disruptive opportunities.In The Innovator's Guide to Growth, Scott Anthony, Mark Johnson, Joseph Sinfield, and Elizabeth Altman take the subject to the next level: implementation. The authors explain how to create this crucial capability for unlocking disruption's transformational power.With a foreword by Christensen, this book provides a set of market-proven tools and approaches to innovation that have been honed through fieldwork with innovative companies like Procter & Gamble, Johnson & Johnson, Pepsi, Intel, Motorola, SAP, and Cisco Systems. The book shows you how to:Follow a market-proven process -- so your company can reliably create blockbuster businessesCreate structures, systems, and metrics -- so the disruptive innovations that will power your firm's future growth receive the funding and personnel needed to succeedCreate a common language of disruptive innovation -- so managers can reach consensus around counterintuitive courses of actionIncisive and practical, this book helps your company take the steps necessary to benefit from disruption -- instead of being eclipsed by it. |
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