English | 2022 | ISBN: 1685076084, 978-1685076085 | 348 pages | True PDF | 6.03 MB Based on the current statistics of the WHO, almost 10 million people lost their lives due to malignant disorders in 2020, implying that one in every six deaths is due to cancer. In parallel, the global population of cancer survivors is also growing, propelled by advances in early detection, diagnosis and treatment methods, but also by demographic aging. More and more cancer patients today decide to use dietary supplements and herbal products in order to enhance their overall health, delay the progression of disease, augment the outcome of conventional therapies, mitigate diagnosis-related depression and anxiety, and alleviate drug-associated side effects, doing it mostly unbeknownst to their health care providers. Such over-the-counter supplements usually contain diverse flavonoids, such as catechins from green tea extracts, isoflavones from soy products, flavanones from citrus oils or silibinin from milk thistle seeds, just to name a few. A variety of flavonoid-rich products are often consumed concurrently with standard cancer therapies, without anticipating and understanding the potential interactions between plant-derived bioactive flavonoids and clinically used anticancer drugs. In this book, diverse effects of these polyphenolic phytochemicals on hormonal and targeted biological cancer therapies are covered, being a reasoned follow-up to the two previous books Plant Flavonoids Affect Cancer Chemotherapeutic Efficacy: A Handbook for Doctors and Patients (2019) and Dietary Flavonoids Interfere with Cancer Radiotherapy (2019). Besides naturally occurring flavonoids, the impact of flavonoid-rich plant extracts as well as semisynthetic derivatives on anticancer activities of co-administered hormonal and targeted drugs are thoroughly discussed, and some indicative recommendations to patients undergoing hormonal cancer therapies or targeted biological cancer therapies are provided. English | 2022 | ISBN: 1119891272 | 451 pages | True PDF | 14.4 MB Get hoppin' with this guide to microbrewing your own beer
English | 2022 | ISBN: 1685077595, 978-1685077594 | 402 pages | True PDF | 20.3 MB Heart failure is an increasingly prevalent syndrome worldwide with a high impact on quality of life and survival. Although there have been great advances in the treatment of this condition that effectively increase survival, mortality remains unacceptably high, exceeding 40% at 5 years, which is worse than a large number of cancers. Furthermore, patients with advanced heart failure are a particular subgroup with higher hospitalizations and mortality, with a short-term survival that can be as low as 50% in the case of cardiogenic shock. Heart transplantation remains the gold standard treatment for these patients when other pharmacological and non-pharmacological interventions have failed, with a 1-year survival of approximately 90%. However, not all patients are suitable candidates for this procedure, and knowing the indications as well as the contraindications for heart transplantation is essential for appropriate patient selection. Heart Transplantation: Indications, Postoperative Management and Long-Term Outcomes is a highly illustrated, didactic book that comprehensively describes the pretransplant assessment of the advanced heart failure patient, the perioperative management of heart transplantation, and the early and late complications of the heart transplant recipient. It also covers special situations in heart transplantation such as Chagas cardiomyopathy, congenital heart disease, hypertrophic/restrictive cardiomyopathy and pediatric heart transplantation. This book is intended for cardiology fellows in training, surgeons, cardiologists, internists, and other health professionals involved in the care of heart transplant patients. English | 2022 | ISBN: 0253062810 | 424 pages | True PDF | 31.37 MB Hearing, Sound, and the Auditory in Ancient Greece represents the first wide-ranging philosophical study of the role of sound and hearing in the ancient Greek world. Because our modern western culture is a particularly visual one, we can overlook the significance of the auditory which was so central to the Greeks. The fifteen chapters of this edited volume explore "hearing" as being philosophically significant across numerous texts and figures in ancient Greek philosophy.
English | 2022 | ISBN: 0674271173 | 337 pages | True PDF | 22.06 MB An American Interest Book of the Year
English | 2022 | ISBN: 1462550517 | 243 pages | True PDF | 6.62 MB When a child has been through an upsetting or stressful event, it can feel overwhelming. Is my child traumatized? Are new behaviors normal, or signs of PTSD? What can I do to make my child feel safe again? In this wise and authoritative guide, psychologist Melissa Goldberg Mintz assures loving parents that the tools necessary for supporting a traumatized child are ones they already possess, from promoting recovery at home, to knowing when professional help is needed. Dr. Goldberg Mintz shares specific, critical information and insights into what trauma looks like at different ages, why some kids exposed to the same event react very differently, how to help a child through trauma triggers, and more. Most important, she shows parents how to ensure that kids don't feel constrained by fear--and can face future challenges with hope and resilience.
English | 2022 | ISBN: 1801810540 | 350 pages | True PDF EPUB | 63.98 MB Learn to design, develop, debug, and deploy technologies by harnessing the full power of Visual Studio 2022 by discovering its new features and exclusive techniques
English | 2021 | ISBN: 1799850153, 978-1799850151 | 470 pages | True PDF EPUB | 26.52 MB From traditional brick and mortar to new start-ups, businesses are harnessing the power of digital enterprise as a cost-effective model to deliver goods and services online. Digital enterprise strategy is adopted for transforming business, streamlining processes, and making the best use of online technologies to enhance interaction with customers and employees and deliver excellent customer experience in real time. Digital enterprises increasingly need digital workers to establish greater digital skills to bear on every activity and to drive management, strategy, and innovation, which are key for digital enterprise transformation.
English | 2021 | ISBN: 1799867765, 978-1799867760 | 478 pages | True PDF EPUB | 32.45 MB ICT has had a huge impact on businesses and organizations in general, with new business models, new marketing channels, and new markets being reached using these technologies. ICT can promote new strategies and enhancers to optimize various aspects of business, but this technology also provides important tools that can empower social entrepreneurship initiatives to develop, fund, and implement new and innovative solutions to social, cultural, and environmental problems. With the upheaval caused by the COVID-19 pandemic and its subsequent impact on the economy, the methods and tools used within this field will be forever impacted. ICTs and the digital economy are huge trends that will affect organizations in several dimensions, such as how to communicate and improve performance. Thus, new perspectives and research are needed to identify the trends emerging in these fields. |