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 English | 2022 | ISBN: 1787758141 | 226 pages | True PDF | 6.32 MB Death anxiety can underlie many different mental health diagnoses at all stages of life, including depressive disorders, panic disorder, health anxiety, specific phobias, OCD, agoraphobia and more. This self-help guide will help you to better understand your fear of death and give you the tools to overcome it.  English | 2022 | ISBN: 1098106067, 978-1098106065 | 275 pages | EPUB | 7.29 MB In many systems, scalability becomes the primary driver as the user base grows. Attractive features and high utility breed success, which brings more requests to handle and more data to manage. But organizations reach a tipping point when design decisions that made sense under light loads suddenly become technical debt. This practical book covers design approaches and technologies that make it possible to scale an application quickly and cost-effectively.  English | 2022 | ISBN: 1284234991 | 750 pages | True EPUB | 117.93 MB Advances in respiratory care over the past years have made a significant impact on the health and well-being of infants, children, and their families. Designed to be the primary text for the 'Neonatal and Pediatric' course as part of the respiratory care core curriculum, Foundations in Neonatal and Pediatric Respiratory Care provides students and practitioners alike with a comprehensive yet reader-friendly resource. In this second edition, the authors recognize the importance of sharing the essential elements of care that are unique to children as they grow and develop and provide the clinician with the knowledge needed to effectively communicate recommendations for therapeutic intervention or changes to the plan of care. This text has contributions in each chapter by national experts who are actively practicing in their subject areas, providing the most relevant evidence-based material and content that has a significant and practical application to current practice. Every new print copy includes Navigate Premier Access that unlocks an interactive eBook, the Heart & Lungs Module, an Equipment Simulator, Anatomy & Physiology Module, additional case studies, test prep, and additional flashcards.  English | 2022 | ISBN: 3527346899 | 365 pages | True PDF | 22.38 MB Learn to master a powerful technology to enable a faster drug discovery workflow  English | 2022 | ISBN: 1487508328 | 274 pages | True PDF EPUB | 8.04 MB With supply chain disruptions increasingly discussed in the media and impacting our daily lives, Flow offers an important framework and solutions for remedying the rampant delays and bottlenecks that exist in global supply chains.  English | 2022 | ISBN: 1119565871 | 642 pages | True PDF | 40.9 MB A concise and practical quick reference for veterinary practitioners dealing with feline emergencies
 English | 2022 | ISBN: 1803230061 | 281 pages | True PDF EPUB | 22.27 MB Learn how to leverage feature stores to make the most of your machine learning models
 English | 2022 | ISBN: 1009160281 | 253 pages | PDF | 5.8 MB Problem-solving is the cornerstone of all walks of scientific research. Fascinating Problems for Young Physicists attempts to clear the boundaries of seemingly abstract physical laws and their tangible effects through a step-by-step approach to physics in the world around us. It consists of 42 problems with detailed solutions, each describing a specific, interesting physical phenomenon. Each problem is further divided into questions designed to guide the reader through, encouraging engagement with and learning the physics behind the phenomenon. By solving the problems, the reader will be able to discover, for example, what the relation is between the mass of an animal and its expected lifetime, or what the efficiency limit is of wind turbines. Intended for first-year undergraduate students and interested high school students, this book develops inquiry-based scientific practice and enables students to acquire the necessary skills for applying the laws of physics to realistic situations.
 English | 2022 | ISBN: 168507555X, 978-1685075552 | 270 pages | True PDF | 11.35 MB Metabolic engineering and biocatalysis aim to produce new value-added products from biological routes through careful and deliberate genetic engineering in different microbial chassis with suitable metabolic repertoire. Hitherto, the endeavor has largely been confined to the production of new products from glucose and a few other well characterized substrates. But, as the bioeconomy gains in importance and the world seeks to explore new sources of carbon as feedstocks, a possibility exists in developing alternative C2 compounds as feedstocks in contrast to the current reliance on C6 (glucose and fructose), C5 (xylose) and C3 (glycerol) substrates. Two potential C2 alternative substrates explored in this work are ethanol and ethylene glycol. Ethanol is a biofuel whose biotechnological potential has not been fully explored. In the first part of the book, the potential of using the NADH generated from a reconstructed ethanol utilization pathway to power a biotransformation reaction is explored in Escherichia coli. Experimental results indicate that ethanol utilization delivers higher biotransformation efficiency compared to state-of-the-art glucose dehydrogenase system, which confirmed theoretical predictions of relative efficiency of the two systems. Next, the book switches attention to ethylene glycol which could be derived as breakdown products of lignocellulosic waste or from plastic waste. Here, the proposal is to demonstrate the potential of an NADH generating ethylene glycol utilization pathway that terminates at glycolate to support biocatalytic reactions in E. coli. Subsequently, the two-step ethylene glycol utilization pathway would be extended to malate and 2-phosphoglycerate to help another biotechnology workhorse, Bacillus subtilis, to grow on ethylene glycol as the sole carbon source. Different connection points to central carbon metabolism would provide a natural experiment to decipher the relative efficiencies of activating tricarboxylic acid cycle and glycolysis in supporting cell growth, and illuminate insights into the relative efficiency and evolutionary importance of different branches of metabolism in B. subtilis. Finally, ethylene glycol utilization would be combined with product formation to help B. subtilis to synthesize green fluorescent protein using flux from the C2 alternative substrate. This system would provide a platform for examining the efficacy of different ethylene glycol utilization pathways and entry points in central carbon metabolism in synthesizing amino acids and proteins. Overall, this book hopes to explore the biotechnological potential of two alternative C2 substrates (ethanol and ethylene glycol) in biocatalysis and metabolic engineering from the substrate utilization perspective.
 English | 2022 | ISBN: 9355510985 | 796 pages | True EPUB | 28.87 MB Linux administration based on hosted virtualization. |
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