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 Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies By Darren S. Miller, Edward M. Bertram, Catherine A. Scougall, Ieva Kotlarski (auth.), Robert K. Hamatake PhD, Johnson Y. N. Lau MD (eds.) 2004 | 572 Pages | ISBN: 1588291081 | PDF | 5 MB Despite the availability of an effective vaccine, there are still 400 million people worldwide who are chronically infected with the hepatitis B and D viruses (HBV and HDV), and more work still needs to be done in all of the key areas of managing the disease. In Hepatitis B and D Protocols, leading investigators and clinicians have joined forces to create a broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, Immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. Taken together, Hepatitis B and D Protocols, Volume 1: Detection, Genotypes, and Characterization and Volume 2: Immunology, Model Systems, and Clinical Studies offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients.  Hematopoietic Stem Cell Protocols By Elaine Dzierzak, Marella de Bruijn (auth.), Christopher A. Klug PhD, Craig T. Jordan PhD (eds.) 2002 | 333 Pages | ISBN: 0896038122 | PDF | 3 MB Hematopoietic stem cells have an enormous clinical importance for bone marrow transplantation, hematopoietic gene therapy, solid organ transplantation, and somatic tissue regeneration. In Hematopoietic Stem Cell Protocols, a group of leading stem-cell investigators describe in detail the key laboratory methods for investigating this critically important cell type. Varied in scope, and richly detailed with step-by-step instructions and notes on the pitfalls to be avoided, these readily reproducible protocols apply hematopoietic stem cells isolated from mouse and human tissues of both embryonic and adult origin. The many approaches described employ not only molecular and cell biology techniques, but also animal model systems, and include hematopoietic stem cell expansion protocols and methods for the purification and genetic modification of stem cells. Many of the protocols are contributed by those researchers who first developed and introduced the procedures to the scientific community. Comprehensive and state-of-the-art, Hematopoietic Stem Cell Protocols offers both novice and experienced investigators alike an invaluable compendium of highly practical techniques for studying a wide variety of stem cell topics, including blood formation, blood-based disease, and such blood cancers as leukemia.
 Heart Solution for Women: A Proven Program to Prevent and Reverse Heart Disease by Mark Menolascino M.D. English | January 29, 2019 | ISBN: 0062842137 | 320 pages | PDF | 4.31 Mb Heart disease remains the number one killer of women, outpacing breast cancer, diabetes, and stroke, with one in four women receiving a diagnosis in her lifetime. And the problem is only getting worse.  Alessandro Portelli, "Hard Rain: Bob Dylan, Oral Cultures, and the Meaning of History " English | ISBN: 0231205929 | 2022 | 200 pages | PDF | 566 KB Bob Dylan's iconic 1962 song "A Hard Rain's A-Gonna Fall" stands at the crossroads of musical and literary traditions. A visionary warning of impending apocalypse, it sets symbolist imagery within a structure that recalls a centuries-old form. Written at the height of the 1960s folk music revival amid the ferment of political activism, the song strongly resembles―and at the same time reimagines―a traditional European ballad sung from Scotland to Italy, known in the English-speaking world as "Lord Randal."  HIV Protocols By James R. Lane (auth.), Nelson L. Michael MD, PhD, Jerome H. Kim MD (eds.) 1999 | 401 Pages | ISBN: 0896033694 | PDF | 30 MB In HIV Protocols, Nelson Michael and Jerome Kim have organized a collection of cutting-edge techniques essential for studying the molecular biology, virology, and immunology of the HIV virus. The methods cover a broad range of research interests, including quantitation of viral genomes, HIV promoter function, B-cell epitope mapping, viral coreceptor usage, and measurements of T-cell function. Special emphasis is accorded to the study of those viral and host immune responses to infection that will be critical to the design of effective preventive vaccines. HIV Protocols is the first HIV methods book to concentrate equally on virology, molecular biology, and immunology, as well as to incorporate methods on chemokine receptor structure and function. Comprehensive and state-of-the-art, the techniques detailed here provide an indispensable framework for unraveling the molecular and immunological aspects of HIV infection.  Ted Benton, "Grasshoppers and Crickets" English | 2012 | ISBN: 0007277245, 0007277237 | EPUB | pages: 400 | 41.4 mb A detailed and up-to-date account of the behavior and ecology of grasshoppers and crickets. In this latest New Naturalist volume, Ted Benton offers a comprehensive account of the appearance, variations, behavior, habitat, life-cycles, and distribution of all the native British species of bush-crickets, crickets, groundhoppers, and grasshoppers. Many details from direct field observation are included, which are published here for the first time. With up-to-date information on newly arrived and recently established species, as well as long-established non-native species-such as the house cricket and greenhouse camel cricket-Benton pays special attention to a key area of evolutionary thought that has stimulated an international research focus on grasshoppers and crickets. Recent approaches to mating and reproduction emphasise differences and even conflicts of interest between males and females. The sexually selected adaptations and counter-adaptations to such conflicts of reproductive interest are used to explain the astonishing diversity of reproductive behavior exhibited by grasshoppers and crickets: male territorial behavior, coercive mating, complex songs, elaborate courtship performances, the donation of edible "nuptial gifts," the reversal of sex-roles, mate-guarding, keeping of "harems" and, in a few species, parental care of the offspring. These chapters provide an introduction to the theoretical issues and an overview of many case studies drawn from research on orthopterans from across the world (but including British species where relevant). A unique DVD features many aspects of the behavior of nearly all British species, including song, conflict, courtship behavior, sex-role reversal, and egg laying. The book is lavishly illustrated with color photographs and line drawings, covering all the British species (including immature stages in most cases), key habitats, and many aspects of behavior.  Gods and Goddesses in Ancient Italy edited by Edward Bispham, Daniele Miano English | December 5, 2019 | ISBN: 1138697559, 1032337486 | True EPUB | 164 pages | 3.3 MB This collection explores the multifaceted nature of the gods and goddesses worshipped in ancient Italy. It examines Italic, Etruscan, and Latin deities in context and in the material remains, and also in the Greco-Roman written record and later scholarship which drew on these texts.
 Goal Setting - The Practical 'How To' Guide : for You, for Others, for Business, for Change by Julie Hogbin English | 2020 | ISBN: N/A | ASIN: B08RWP2BLP | 151 pages | EPUB | 0.88 Mb Goal Setting - The Practical 'How To' Guide  George Christou, "Global Networks and European Actors " English | ISBN: 0367720809 | 2021 | 234 pages | EPUB | 2 MB This book examines the ability of the EU and European actor networks to coherently and effectively navigate, manage, and influence debates and policy on the international stage. It also questions whether increasing complexity across a range of critical global issues and networks has affected this ability.  John P. Payne, "Germany Today (RLE: German Politics): Introductory Studies " English | ISBN: 1138847887 | 2014 | 198 pages | EPUB | 1278 KB This book, originally published in 1971, provides clear analysis of German affairs at the end of the 1960s. Without neglecting the historical dimension of recent developments, it examines some of the problems the German people faced in the post-war years. Written by experts, but nonethless in an accessible style the essays in this book give an insight into the methods of particular disciplines such as history, economics, politics or sociology whilst offering an introduction to many aspects of German life. |
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