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 Free Download Think Like a CTO by Alan Williamson English | 2023 | ISBN: 1617298859 | 320 pages | True PDF | 13.34 MB  Free Download Therapeutic potential of Cell Cycle Kinases in Breast Cancer English | 2023 | ISBN: 9811989109 | 390 Pages | PDF EPUB (True) | 46 MB This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.
 Free Download Thomas Hughes, "The scouring of the White Horse: or, The long vacation ramble of a London clerk " English | ISBN: 1975680839 | 2017 | 116 pages | EPUB | 380 KB Thomas Hughes QC (20 October 1822 - 22 March 1896) was an English lawyer, judge, politician and author. He is most famous for his novel Tom Brown's School Days (1857), a semi-autobiographical work set at Rugby School, which Hughes had attended. It had a lesser-known sequel, Tom Brown at Oxford (1861). Hughes had numerous other interests, in particular as a Member of Parliament, in the British co-operative movement, and in a settlement in Tennessee reflecting his values. Early life Hughes was the second son of John Hughes, editor of the Boscobel Tracts (1830) and was born in Uffington, Berkshire (now Oxfordshire). He had six brothers, and one sister, Jane Senior who later became Britain's first female civil servant. At the age of eight he was sent to Twyford School, a preparatory public school near Winchester, where he remained until the age of eleven. In February 1834 he went to Rugby School, which was then under the celebrated Thomas Arnold, a contemporary of his father at Oriel College, Oxford. Hughes excelled at sports rather than in scholarship, and his school career culminated in a cricket match at Lord's Cricket Ground. In 1842 he went on to Oriel College, and graduated B.A. in 1845. At Oxford, he played cricket for the university team in the annual University Match against Cambridge University, also at Lord's, and a match that is still now regarded as first-class cricket. Legal career Hughes was called to the bar in 1848, became Queen's Counsel in 1869 and a bencher in 1870. He was appointed to a county court judgeship in the Chester district in July 1882......... Richard "Dickie" Doyle (18 September 1824 - 10 December 1883) was a notable illustrator of the Victorian era. His work frequently appeared, amongst other places, in Punch magazine; he drew the cover of the first issue, and designed the magazine's masthead, a design that was used for over a century. Biography Born at 17 Cambridge Terrace, London, one of seven children of Irish cartoonist John Doyle(known as 'H.B'), a noted political caricaturist, Doyle had three brothers, James, Charles and Henry Edward Doyle, who were also artists. The young Doyle had no formal art training other than his father's studio, but from an early age displayed a gifted ability to depict scenes of the fantastic and grotesque. Throughout his life he was fascinated by fairy tales. He produced his first complete illustrated book, Home for the Holidays, when he was twelve; it was published posthumously in 1887. He joined the staff of Punch in 1843 aged 19, remaining there for seven years. He was the uncle of Sir Arthur Conan Doyle, author of the Sherlock Holmes stories.....  Free Download Anke Fischer-Kattner, "The World of the Siege" English | 2019 | pages: 326 | ISBN: 9004395687 | PDF | 5,8 mb The World of the Siege examines relations between the conduct and representations of early modern sieges. The volume offers case studies from various regions in Europe (England, France, the Low Countries, Germany, the Balkans) and throughout the world (the Chinese, Ottoman and Mughal Empires), from the 15th century into the 18th. The international contributors analyse how siege narratives were created and disseminated, and how early modern actors as well as later historians made sense of these violent events in both textual and visual artefacts. . The volume's chronological and geographical breadth provides insight into similarities and differences of siege warfare and military culture across several cultures, countries and centuries, as well as its impact on both combatants and observers.
 Free Download Brennan C. Pursell, "The Winter King: Frederick V of the Palatinate and the Coming of the Thirty Years' War" English | ISBN: 0754634019 | 2003 | 356 pages | EPUB | 2 MB Elector Palatinate Frederick V - the Winter King - would be an insignificant figure in the history of Europe were it not for the tremendous conflagration that he helped to ignite. Frederick's conflict with Holy Roman Emperor Ferdinand II over the throne of Bohemia plunged Europe into thirty years of savage violence, fiery devastation, and terrible privation during the first half of the seventeenth century. More than simply a biographical study of Frederick, The Winter King provides a fresh and compelling study into the causes of the Thirty Years' War. Examining the early stages of the war through the locus of Frederick, it reconciles the forces of confession, conscience and constitutionalism that affected Frederick's decision making at critical junctures throughout the crisis. By placing constitutionalism rather than religion at the centre of events, it offers a subtle yet convincing new account of the conflict. Drawing on political and personal correspondence, backed up with a wealth of archival and secondary sources, Dr Pursell presents Frederick's choices and alternatives and interprets his words and responses to them. Considering the war from Frederick's perspective he argues convincingly that the war is best understood not simply as a struggle between Protestant and Catholic powers, but rather as an extended constitutional conflict, entwining religious and political factors, fought within the Holy Roman Empire.
 Free Download The United States-Mexico Border: The Controversial History and Legacy of the Boundary between America and Mexico by Charles River Editors English | January 30, 2017 | ISBN: N/A | ASIN: B01N39XCJU | 74 pages | EPUB | 1.40 Mb *Includes pictures  Free Download The Unnoticed Entrepreneur by James, Jim; English | 2023 | ISBN: 0857089641 | 371 pages | True PDF EPUB | 8.63 MB  Free Download The Twenty Second Happiness Hack: How This One 20-Second Activity Can Make You Feel Better and Happier, Fast! (5 Minute Happiness Hacks Series) by Life Lab Academy English | February 18, 2022 | ISBN: N/A | ASIN: B09SWRG7PK | EPUB | 0.11 Mb Become happier in just 20 seconds!In this guide you will learn about a really simple yet incredibly effective tactic that can help you become happier, fast!  Free Download The Triple-Whammy Happiness Hack: How This One Small Thing Can Easily Make You Happier, and Do So Super Fast! (5 Minute Happiness Hacks Series) by Life Lab Academy English | February 17, 2022 | ISBN: N/A | ASIN: B09STQZGBP | EPUB | 0.10 Mb Happiness can be hacked, and you are about to learn how!  Free Download The Tiberian Pronunciation Tradition of Biblical Hebrew, Volume 2 By Geoffrey Khan 2020 | 366 Pages | ISBN: 1783748575 | PDF | 7 MB The form of Biblical Hebrew that is presented in printed editions, with vocalization and accent signs, has its origin in medieval manuscripts of the Bible. The vocalization and accent signs are notation systems that were created in Tiberias in the early Islamic period by scholars known as the Tiberian Masoretes, but the oral tradition they represent has roots in antiquity. The grammatical textbooks and reference grammars of Biblical Hebrew in use today are heirs to centuries of tradition of grammatical works on Biblical Hebrew in Europe. The paradox is that this European tradition of Biblical Hebrew grammar did not have direct access to the way the Tiberian Masoretes were pronouncing Biblical Hebrew.In the last few decades, research of manuscript sources from the medieval Middle East has made it possible to reconstruct with considerable accuracy the pronunciation of the Tiberian Masoretes, which has come to be known as the 'Tiberian pronunciation tradition'. This book presents the current state of knowledge of the Tiberian pronunciation tradition of Biblical Hebrew and a full edition of one of the key medieval sources, Hidāyat al-Qāriʾ 'The Guide for the Reader', by ʾAbū al-Faraj Hārūn. It is hoped that the book will help to break the mould of current grammatical descriptions of Biblical Hebrew and form a bridge between modern traditions of grammar and the school of the Masoretes of Tiberias.Links and QR codes in the book allow readers to listen to an oral performance of samples of the reconstructed Tiberian pronunciation by Alex Foreman. This is the first time Biblical Hebrew has been recited with the Tiberian pronunciation for a millennium. |
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