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From its inception in 1853 until its demise in 1907, the compulsory smallpox vaccine was fiercely resisted, largely by members of the working class who interpreted it as an infringement of their rights as citizens and a violation of their children's bodies. Nadja Durbach contends that the anti-vaccination movement is historically significant not only because it was arguably the largest medical resistance campaign ever mounted in Europe but also because it clearly articulated pervasive anxieties regarding the integrity of the body and the role of the modern state. Analyzing historical documents on both sides of the vaccination debate, Durbach focuses on the key events and rhetorical strategies of the resistance campaign. She shows that those for and against the vaccine had very different ideas about how human bodies worked and how best to safeguard them from disease. 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