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In particular, a great deal of attention has been devoted to the problem of extracting "reliable" information from databases containing pieces of information inconsistent with regard to some integrity constraints. In this manuscript, the problem of extracting consistent information from relational databases violating integrity constraints on numerical data is addressed. Aggregate constraints defined as linear inequalities on aggregate-sum queries on input data are considered. The notion of repair as consistent set of updates at attribute-value level is exploited, and the characterization of several data-complexity issues related to repairing data and computing consistent query answers is provided. Moreover, a method for computing "reasonable" repairs of inconsistent numerical databases is introduced, for a restricted but expressive class of aggregate constraints. 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The present volume describes the intricacies involved in these processes, including the in?uence of prorenin/renin, angiotensin II, angiotensin (1-7), and aldosterone on cardiac and vascular functions as well as their involvement in the generation of cardiovascular diseases. Fundamental aspects like intracellular signaling, regulation of cell volume in the failing heart, and the presence of an intracrine renin angiotensin system are discussed. Moreover, the role of the mineralocorticoid receptor as an important c- ponent of the intracrine renin angiotensin system and as a regulator of extracellular action of angiotensin II is described, reinforcing the view that aldosterone inhibitors are helpful in the treatment of heart failure and hypertension. Let us hope the imp- tant topics included here motivate basic and clinical investigators and contribute to the development of new therapeutic approaches for cardiovascular diseases. We want to thank the distinguished authors and Humana Press for the opportunity to publish this important book. Walmor C. DeMello Edward Frohlich v Contents 1 Systemic Versus Local Renin Angiotensin Systems. An Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Walmor C. DeMello and Richard N. Re 2 Clinical Import of the Local Renin Angiotensin Aldosterone Systems . . . . . . . . . . . . . . . . . . . . . . . . . 7 Edward D. Frohlich 3 Renin, Prorenin, and the (Pro)Renin Receptor . . . . . . . . . . . 15 Genevieve Nguyen and Aurelie Contrepas 4 Local Renin Angiotensin Systems in the Cardiovascular System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Richard N.  Free Download Renewable Energy Options for Power Generation and Desalination English | 2024 | ISBN: 3031534360 | 381 Pages | PDF EPUB (True) | 145 MB This book examines simultaneous power generation and desalination driven by renewable energy systems. 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