![]() |
![]() Free Download DuMont direkt Reiseführer Sydney Deutsch | 2024 | ISBN: 3616001021 | 126 Pages | PDF (True) | 13 MB Kaum eine andere Metropole hat einen so hohen Freizeitwert wie Australiens heimliche Hauptstadt: Sonne und Meer verlocken am Bondi Beach zum Schwimmen und Surfen, ausgedehnte Parkanlagen wie die Royal Botanic Gardens finden sich selbst im Zentrum.Mit den 15 Direktkapiteln des Reiseführers von Roland Dusik können Sie sich zwanglos unter die gut gelaunten und weltoffenen Sydneysider mischen, direkt in das entspannte Stadtleben eintauchen und die Highlights und Hotspots kennenlernen: die kosmopolitische und bunte Altstadt, das legendäre Opera House und die Harbour Bridge, die hippe Shoppingmeile Oxford Street, Chinatown und Aborigines-Kunst.In eigenen Kapiteln erfahren Sie, wo es sich in fremden Betten gut schläft, wo Sie glücklich satt werden, wohin die Sydneysider zum Stöbern und Entdecken gehen und wohin es sie zieht, wenn die Nacht beginnt.Mit den Übersichtskarten, genauen Stadtteilplänen und dem separaten großen Cityplan können Sie sich nach Lust und Laune durch Sydney treiben lassen. ![]() Free Download Daniel Sipos, "Drupal 9 Module Development - Third Edition: Get up and running with building powerful Drupal modules and applications" English | 2020 | pages: 627 | ISBN: 1800204620 | PDF | 6,9 mb Build and extend flexible Drupal sites and applications with this up-to-date, expert guide to Drupal 9 module development ![]() Free Download Jordan Sonnenblick, "Drums, Girls, and Dangerous Pie" English | 2004 | pages: 304 | ISBN: 0545722861, 0439755190 | EPUB | 0,2 mb A brave and beautiful story that will make readers laugh, and break their hearts at the same time. Now with a special note from the author! ![]() Free Download Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays English | 2024 | ISBN: 3031355288 | 2810 Pages | PDF EPUB (True) | 277 MB Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters. ![]() Free Download Drug Development Supported by Informatics English | 2024 | ISBN: 9819748275 | 625 Pages | PDF EPUB (True) | 111 MB This book describes the state-of-the-art of chemoinformatics, bioinformatics, materials informatics and measurement/metrology informatics to develop drugs with desired activity or physicochemical properties and to optimize the functionality, efficacy, safety and quality of the compounds for drugs. Recently, "AI drug discovery", drug discovery research utilizing artificial intelligence technology such as machine learning, has attracted much attention. This book provides an overview of the four applied informatics fields and their applications in drug development for a wide spectrum of readers from learners to professional scientists in academia and industry. It focuses on the basic research stage of drug development with contributions from experts at the forefront of these fields. The authors hope that this book will be of assistance to explore new opportunities for collaboration between pharmaceutical science and informatics. ![]() Free Download Drug Delivery Strategies in Neurological Disorders: Challenges and Opportunities by Awanish Mishra, Hitesh Kulhari English | February 29, 2024 | ISBN: 9819968062 | 471 pages | MOBI | 7.05 Mb This book comprehensively reviews the recent progress in their pathogenesis and management approaches for neurological disorders. It focuses on understanding the molecular mechanism, pathology, novel nanotechnology-based approaches against stroke, Alzheimer's disease, Parkinson disease, Huntington's disease, Multiple sclerosis, and Epilepsy. The book provides the basic understanding about the development and progression of these diseases, and recent pharmacotherapeutic approaches for their management. It also discusses challenges in drug development for neurological disorders, including preclinical models of disorders, the need for drugs to cross the blood-brain-barrier, and limited understanding of relevant pathophysiology. The book also focuses on different conventional and novel strategies for drug delivery in neurological disorders. Towards the end, the book reviews the applications of nanotechnology for the diagnosis of neurological disorders. One of the chapters is focused onthe role of herbal actives in the treatment of neurological disorders. Finally, a chapter is included on nanotechnology-based approaches for diagnosis of neurological disorders. This book is a useful resource for students and researchers of pharmaceutical sciences, life sciences, material sciences, and nanosciences. ![]() Free Download Driving Cost-Effective Innovation with Concurrent Systems: Strategy, Process, Organization & Tools/Technologies English | 2025 | ISBN: 1786343894 | 837 Pages | PDF (True) | 12 MB ![]() Free Download Drive: Scraping By in Uber's America, One Ride at a Time by Jonathan Rigsby English | May 14, 2024 | ISBN: 0807007935 | 200 pages | PDF | 1.34 Mb One father, 3 years, and thousands of rides ![]() Free Download Dreaming and Memory: Philosophical Issues English | 2024 | ISBN: 3031682033 | 392 Pages | PDF EPUB (True) | 11 MB This edited volume is the first systematic philosophical investigation of the complex and multifarious relationships between dreaming and memory. Featuring fifteen contributions by leading researchers, it explores a range of issues that arise when dreaming and memory are considered together. What does one remember when one remembers what one dreamt, and what is it for a memory of a dream to be accurate? What are the phenomenological, cognitive, and epistemic similarities and dissimilarities between dreaming and remembering? How does the self figure in dreams and memories? The book will serve as an indispensable resource both for philosophers interested in dreaming or memory and for their philosophically-minded colleagues in empirical disciplines and will provide an invaluable starting point for advanced students in need of a snapshot of the state of the art in philosophical research on dreaming and memory. ![]() Free Download Serge Kahili King, "Dreaming Techniques: Working with Night Dreams, Daydreams, and Liminal Dreams" English | 2020 | pages: 240 | ISBN: 1591433886 | EPUB | 1,4 mb Harness the transformative power of night dreams, half-awake dreams, and daydreams for healing, manifestation, and insight |