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 Free Download Mucins: Methods and Protocols By Karine Rousseau, Dallas M. Swallow (auth.), Michael A. McGuckin, David J. Thornton (eds.) 2012 | 329 Pages | ISBN: 1617795127 | PDF | 5 MB Epithelial mucins are large complex cell surface and secreted glycoproteins produced by mucosal epithelial cells. In, Mucins: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study Mucins. These include methods and techniques for the best approaches to analysing each specific area of mucin biochemistry, physiology and biophysics before providing individual detailed experimental protocols together with troubleshooting and interpretation tips. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Mucins: Methods and Protocols is designed to be a useful resource for those entering the mucin field and to facilitate those already studying mucins to broaden their experimental approaches to understanding mucosal biology.  Free Download mTOR: Methods and Protocols By Thomas Weichhart (auth.), Thomas Weichhart (eds.) 2012 | 464 Pages | ISBN: 1617794295 | PDF | 7 MB Since its discovery, the mammalian target of rapamycin (mTOR) has been shown to regulate many critical molecular processes in eukaryotes such as metabolism, growth, survival, aging, synaptic plasticity, memory, and immunity. In mTOR: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study mTOR. These include methods and techniques used for the study of the mTOR pathway and potential therapeutic applications of mTOR inhibitors such as, immunosuppressive and anticancer agents. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, mTOR: Methods and Protocols seeks to aid scientists in the further study of this crucially important molecule ranging from the analysis of signal transduction events within a cell to the assessment of complex human diseases such as metabolic disorders or cancer.  Free Download Paul J. Heer, "Mr. X and the Pacific: George F. Kennan and American Policy in East Asia" English | ISBN: 1501711148 | 2018 | 320 pages | PDF | 7 MB George F. Kennan is well known as the preeminent American expert on the Soviet Union during the Cold War and the author of the doctrine of containment. In Mr. X and the Pacific, Paul J. Heer chronicles and assesses Kennan's work in affecting US policy toward East Asia.  Free Download Moving in the Margins: Desert Travel and Power in Medieval Central Asia by Paul D Wordsworth English | 2025 | ISBN: 9004534873 | 367 Pages | True PDF | 58 MB  Free Download Mouse Development: From Oocyte to Stem Cells By Hugh J. Clarke (auth.), Jacek Z. Kubiak (eds.) 2012 | 440 Pages | ISBN: 3642304052 | PDF | 6 MB The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.
 Free Download Mound Centers and Seed Security: A Comparative Analysis of Botanical Assemblages from Middle Woodland Sites in the Lower Illinois Valley By Natalie G. Mueller (auth.) 2013 | 67 Pages | ISBN: 1461459206 | PDF | 2 MB At Middle Woodland sites in the eastern United States, excavations have uncovered naturalistic art worked on exotic materials from points as distant Wyoming, Ontario, and the Gulf Coast, revealing a network of ritual exchange referred to as the Hopewell phenomenon. Simultaneously, Middle Woodland societies developed the earliest agricultural system in eastern North American using now-extinct native cultivars. Mound Centers and Seed Security: A Comparative Analysis of Botanical Assemblages from Middle Woodland Sites in the Lower Illinois Valley integrates an interpretation of these two historical trends.Unlike most journal articles on related subjects, the volume includes a lengthy review of literature on both Hopewell studies and Middle Woodland agriculture, making it a useful resource for researchers starting out in either field. Synthesizing both original research and research reported in archaeological "grey literature", Mound Centers and Seed Security: A Comparative Analysis of Botanical Assemblages from Middle Woodland Sites in the Lower Illinois Valley is a valuable tool for researchers and teachers alike.
 Free Download RoseAnne O′Brien Vojtek, "Motivate! Inspire! Lead!: 10 Strategies for Building Collegial Learning Communities" English | ISBN: 1412928060 | 2009 | 344 pages | EPUB | 5 MB Incorporating motivational theory and the authors′ administrative experience, this resource presents 10 strategies for developing a collegial learning community through positive interdependence, reciprocal relationships, and mutual responsibility.
 Free Download Mosquito Vectors of Japanese Encephalitis Virus from Northern India: Role of BPD hop cage method By Bina Pani Das (auth.) 2013 | 144 Pages | ISBN: 8132208609 | PDF | 6 MB Japanese Encephalitis (JE), a mosquito borne disease, is the leading cause of viral encephalitis in 14 Asian countries due to its epidemic potential, high case fatality rate and increased possibility of lifelong disability in patients who recover from this dreadful disease. In spite of seriousness of the disease, still only few books are available for ready reference. Hence, this book will be useful for students, entomologists, paramedical staff and vector control managers in public health. The objective of the book is to disseminate the knowledge gained by the author from ecological studies on JE vectors undertaken in 2 endemic and 2 non endemic areas of Northern India over a period of last 15 years (1998-2012) of research in the field of ecology of mosquito vectors of JE virus initially at National Institute of Communicable Diseases (Ministry of Health & Family Welfare, Government of India), Delhi and later at Jamia Millia Islamia, a Central University, Delhi, to anyone who wishes to curtail death of children due to this dreaded disease. Of the thousand suspected JE deaths in India annually, more than 75% is contributed by Northern India wherein disease transmission failed to be explained based on entomological evidence due to inadequate mosquito surveillance tool used in determining JE vector density. In order to overcome the above problem, Dr Bina Pani Das, the author of this book, developed "BPD hop cage method", a simple, cost effective, and operationally feasible surveillance tool specially designed to capture predominantly day resting adult Cx. tritaeniorhynchus mosquitoes, the principal JE vector species in the country from land and aquatic vegetation.  Free Download Morphology and Evolution of Turtles By Robert L. Carroll (auth.), Donald B. Brinkman, Patricia A. Holroyd, James D. Gardner (eds.) 2013 | 580 Pages | ISBN: 9400743084 | PDF | 30 MB This volume celebrates the contributions of Dr. Eugene Gaffney to the study of turtles, through a diverse and complementary collection of papers that showcases the latest research on one of the most intriguing groups of reptiles. A mix of focused and review papers deals with numerous aspects of the evolutionary history of turtles, including embryonic development, origins, early diversification, phylogenetic relationships, and biogeography. Moreover it includes reports on important but poorly understood fossil turtle assemblages, provides historical perspectives on turtle research, and documents disease and variation in turtles. With its broad scope, which includes descriptions of material and new taxa from Australia, Asia, and Europe, as well as North and South America, this work will be an essential resource for anyone interested in the morphology and evolution of turtles. "This volume's breadth of time, geography, and taxonomic coverage makes it a major contribution to the field and a 'must have' for all vertebrate paleontologists.", James F. Parham, California State University, CA, USA "A comprehensive and sweeping overview of turtle evolution by the top experts in the field that will interest everyone curious about these unique reptiles." Jason S. Anderson, University of Calgary, Canada "An invaluable addition to the literature that covers the full spectrum of approaches toward understanding the evolution of these noble creatures." Ann C. Burke, Wesleyan University, CT , USA "A truly comprehensive volume that both the student of fossil turtles, as well as the general reader interested in these enigmatic creatures, will find fascinating." Tyler Lyson, Yale University, CT, USA  Free Download Morphofunctional Aspects of Tumor Microcirculation By Domenico Ribatti (auth.) 2012 | 116 Pages | ISBN: 940074935X | PDF | 3 MB Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like normal blood vessels, they consist of endothelial cells, mural cells and their enveloping basement membrane. Common features, irrespective of their origin, size and growth pattern, are absent hierarchy, formation of large-caliber sinusoidal vessels, markedly heterogeneous density, increased permeability, decreased and abnormal pericyte-endothelial cell adhesion, irregular basement membrane structure, and the incorporation of bone-marrow-derived endothelial progenitor cells in the microvasculature. A number of specific tumor endothelial markers have been identified, as well as chromosomal abnormalities. These markers may be used to deliver drugs specifically and selectively to the tumor microvasculature. |
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