Free Download Shaun Fynn, "Chandigarh Revealed: Le Corbusier's City Today" English | ISBN: 1616895810 | 2017 | 240 pages | PDF | 37 MB In 1950, Indian prime minister Jawaharlal Nehru invited legendary French-Swiss architect Le Corbusier to embark on one of the greatest experiments in urban planning history: to build a new capital-Chandigarh, a city whose monumental modernism promised to free India from the fetters of colonial tradition. Free Download Kristien Hens, "Chance Encounters: A Bioethics for a Damaged Planet" English | ISBN: 1800648499 | 2022 | 268 pages | EPUB | 12 MB In this rigorous and necessary book, Kristien Hens brings together bioethics and the philosophy of biology to argue that the role of the philosopher in scientific research is ethically necessary, and that it can also improve the quality and coherence of the research itself, ensuring that concepts employed, be it genes or autism or development, are used consistently and thoughtfully across interdisciplinary projects. She argues that chance and uncertainty play a central role in bioethics, and we must therefore focus as much on what we know as on what we create: in describing organisms and practices we make the world. As such, this is necessarily an ethical activity.
Free Download Challenges Between Competition and Collaboration: The Future of the European Manufacturing Industry By Peter Sachsenmeier, Martin Schottenloher (auth.), Peter Sachsenmeier, Martin Schottenloher (eds.) 2003 | 326 Pages | ISBN: 364207278X | PDF | 8 MB European manufacturing industries are changing fast. Amid the pressures of globalisation, emerging markets and shifting geographical patterns of consumption and production, competition and collaboration need to be redefined. The book contains roadmaps for survival in the emerging global competitive arena by and for practitioners, as well as concrete examples and theoretical studies across industries. New forms of cooperation are analysed which combine intensive collaboration with high competition in networks of excellence among suppliers, manufacturers and customers. The success factors for such industrial networks are described in detail, as well as their benefits and potential risks. In a multidisciplinary approach, the book draws on parallels from other fields and disciplines in order to explore the many facets of competition and collaboration. Free Download Cereal Genomics II By Pushpendra K. Gupta, Rajeev K. Varshney (auth.), Pushpendra K. Gupta, Rajeev K. Varshney (eds.) 2013 | 438 Pages | ISBN: 9400764006 | PDF | 6 MB "Cereal Genomics" published in 2004 served the purpose of collecting all information on cereal genomics at one place and was well received by the cereal workers through-out the world. The last eight years have witnessed significant advancement in the field of cereal genomics. For instance, high-density genetic maps, physical maps, QTL maps and even draft genome sequence have become available for several cereal species. Furthermore, the next generation sequencing (NGS) technologies have revolutionized genomics research, so that it is possible now to sequence genomes of hundreds or thousands of accessions of an individual cereal crop. Significant amounts of data generated using these NGS technologies created a demand for computational tools to analyse this massive data. In view of these developments, the Editors realised that there was a need to have an updated volume on the present status and future prospects of cereal genomics. These developments related to technology and the tools have been documented in this volume, thus supplementing our earlier edited volume "Cereal Genomics". "Cereal Genomics II" discusses advances in cereal genomics research made during the last eight years, and presents state-of-art cereal genomics and its utilization involving both basic research such as comparative genomics and functional genomics, and applied research like QTL mapping and molecular breeding.
Free Download Patrick Sean Quinn, "Ceramic Petrography: The Interpretation of Archaeological Pottery & Related Artefacts in Thin Section" English | ISBN: 1905739591 | 2013 | 260 pages | PDF | 127 MB Thin section ceramic petrography is a versatile interdisciplinary analytical tool for the characterization and interpretation of archaeological pottery and related artefacts, including ceramic building materials, refractories and plaster. Using over 200 colour photomicrographs of thin sections from a diverse range of artefacts, archaeological periods and geographic regions, this book illustrates the spectrum of compositional and microstructural phenomena that occur within ancient ceramics under the micro-scope and provides comprehensive guidelines for their study within archaeology. The book is structured according to the main steps involved in the analysis and interpretation of archaeological ceramic thin sections, including classification, characterization, the determination of provenance and the reconstruction of manufacturing technology. It can be used as a reference manual for microscope research as well as a course book for specialist training on thin section petrography and archaeological ceramic analysis. Free Download Cellular Trafficking of Cell Stress Proteins in Health and Disease By Lawrence E. Hightower, Emily J. Noonan (auth.), Brian Henderson, A. Graham Pockley (eds.) 2012 | 298 Pages | ISBN: 940074739X | PDF | 4 MB Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes. In the former, molecular chaperone trafficking can occur between the various cellular compartments, with concomitant movement of other proteins. Such events can also result in the release of molecular chaperones from cells. In bacteria, molecular chaperones are involved in the trafficking of other proteins and are themselves released into the external milieu. The increasing appreciation of the role of molecular chaperones and Protein-Folding Catalysts in the interplay between bacteria and the cells of their hosts is now an important area of research for understanding the mechanisms of infectious diseases. This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease. Free Download Cellular Physiology and Metabolism of Physical Exercise By Livio Luzi (auth.), Livio Luzi (eds.) 2012 | 180 Pages | ISBN: 884702417X | PDF | 2 MB The book covers areas of cellular physiology and metabolism that are of interest to scientists involved in research in diabetes and metabolic diseases. Some chapters of the book are specifically research-oriented, as all the authors are actively practicing either bench or clinical research in the area. Nonetheless, since the work is fully comprehensive of the discipline, it is also suitable for university classes of graduate and undergraduate students. In particular, the book discusses classical aspects of cellular physiology and the metabolism of physical exercise, as well as novel topics like exercise in transplantation and exercise in beta-cell failure, which mark the frontiers of research in sport-related sciences and research. Exercise physiologists, biologists and physicians are the specific professional and academic targets of this work. The team of authors together with the editor are world-renowned experts in the field of physiology and metabolism applied to sport sciences. Free Download Cell-Penetrating Peptides: Methods and Protocols By Maria Lindgren, Ülo Langel (auth.), Ülo Langel (eds.) 2011 | 586 Pages | ISBN: 1607619180 | PDF | 8 MB In recent years, a new understanding of cell-penetrating peptides has emerged, helping researchers to expand beyond a number of long-held dogmas. In Cell-Penetrating Peptides: Methods and Protocols, expert researchers explore the latest information on cell-penetrating peptides (CPPs), providing insight into the most important and contemporary areas of CPP research. Chapters address the historical background of CPP studies, provide an overview of the growing field of research, investigate methods for testing CPP mechanisms, present a summary of methods that attempt to use properties of CPPs to study biochemical intracellular mechanisms of interaction and signal transduction, and include new ideas for turning CPP-based strategies into drugs. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Innovative and current, Cell-Penetrating Peptides: Methods and Protocols is an essential guide that allows researchers to study intracellular mechanisms in new ways, and to promote the future development of novel drugs. Free Download Cell Signaling Reactions: Single-Molecular Kinetic Analysis By Michio Hiroshima, Yasushi Sako (auth.), Yasushi Sako, Masahiro Ueda (eds.) 2011 | 330 Pages | ISBN: 9048198631 | PDF | 10 MB This book encompasses the exciting developments and challenges in the fast-moving and rapidly expanding research field of single-molecule kinetic analysis of cell signaling that promises to be one of the most significant and exciting areas of biological research for the foreseeable future. Cell signaling is carried out by complicated reaction networks of macromolecules, and single-molecule analyses has already demonstrated its power to unravel complex reaction dynamics in purified systems. To date, most of the published research in the field of single-molecule processes in cells, focus on the dynamic properties (translational movements of the centre of mass) of biological molecules. However, we hope that this book presents as many kinetic analyses of cell signaling as possible. Although single-molecule kinetic analysis of cellular systems is a relatively young field when compared with the analysis of single-molecule movements in cells, this type of analysis is highly important because it directly relates to the molecular functions that control cellular behavior and in the future, single-molecule kinetic analysis will be largely directed towards cellular systems. Thus, we hope that this book will be of interest to all those working in the fields of molecular and cell biology, as well as biophysics and biochemistry. Free Download Cell Senescence: Methods and Protocols By Andrew R. J. Young, Masako Narita, Masashi Narita (auth.), Lorenzo Galluzzi, Ilio Vitale, Oliver Kepp, Guido Kroemer (eds.) 2013 | 538 Pages | ISBN: 162703238X | PDF | 8 MB Cell senescence is the process whereby cells permanently lose the possibility to proliferate without undergoing cell death, and occurs in a plethora of distinct model organisms. In Cell Senescence: Methods and Protocols, expert researchers in the field detail the methods thatare now commonly used to study cell senescence, in model organisms encompassing bacteria, fungi, worms, flies, zebrafish, and mammalian cells. These techniques cover the study of all the morphological, biochemical and functional manifestations of senescence at the cellular level andinclude protocols for population analyses and high-throughput approaches in suitable model organisms. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. |