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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drums, Girls, and Dangerous Pie
Free Download Jordan Sonnenblick, "Drums, Girls, and Dangerous Pie"
English | 2004 | pages: 304 | ISBN: 0545722861, 0439755190 | EPUB | 0,2 mb
A brave and beautiful story that will make readers laugh, and break their hearts at the same time. Now with a special note from the author!

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drug Discovery and Evaluation (3rd Edition)
Free Download Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
English | 2024 | ISBN: 3031355288 | 2810 Pages | PDF EPUB (True) | 277 MB
Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters.

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drug Development Supported by Informatics
Free Download Drug Development Supported by Informatics
English | 2024 | ISBN: 9819748275 | 625 Pages | PDF EPUB (True) | 111 MB
This book describes the state-of-the-art of chemoinformatics, bioinformatics, materials informatics and measurement/metrology informatics to develop drugs with desired activity or physicochemical properties and to optimize the functionality, efficacy, safety and quality of the compounds for drugs. Recently, "AI drug discovery", drug discovery research utilizing artificial intelligence technology such as machine learning, has attracted much attention. This book provides an overview of the four applied informatics fields and their applications in drug development for a wide spectrum of readers from learners to professional scientists in academia and industry. It focuses on the basic research stage of drug development with contributions from experts at the forefront of these fields. The authors hope that this book will be of assistance to explore new opportunities for collaboration between pharmaceutical science and informatics.

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drug Delivery Strategies in Neurological Disorders Challenges and Opportunities
Free Download Drug Delivery Strategies in Neurological Disorders: Challenges and Opportunities by Awanish Mishra, Hitesh Kulhari
English | February 29, 2024 | ISBN: 9819968062 | 471 pages | MOBI | 7.05 Mb
This book comprehensively reviews the recent progress in their pathogenesis and management approaches for neurological disorders. It focuses on understanding the molecular mechanism, pathology, novel nanotechnology-based approaches against stroke, Alzheimer's disease, Parkinson disease, Huntington's disease, Multiple sclerosis, and Epilepsy. The book provides the basic understanding about the development and progression of these diseases, and recent pharmacotherapeutic approaches for their management. It also discusses challenges in drug development for neurological disorders, including preclinical models of disorders, the need for drugs to cross the blood-brain-barrier, and limited understanding of relevant pathophysiology. The book also focuses on different conventional and novel strategies for drug delivery in neurological disorders. Towards the end, the book reviews the applications of nanotechnology for the diagnosis of neurological disorders. One of the chapters is focused onthe role of herbal actives in the treatment of neurological disorders. Finally, a chapter is included on nanotechnology-based approaches for diagnosis of neurological disorders. This book is a useful resource for students and researchers of pharmaceutical sciences, life sciences, material sciences, and nanosciences. ​

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Driving Cost–Effective Innovation with Concurrent Systems
Free Download Driving Cost-Effective Innovation with Concurrent Systems:
Strategy, Process, Organization & Tools/Technologies

English | 2025 | ISBN: 1786343894 | 837 Pages | PDF (True) | 12 MB

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drive Scraping By in Uber's America, One Ride at a Time
Free Download Drive: Scraping By in Uber's America, One Ride at a Time by Jonathan Rigsby
English | May 14, 2024 | ISBN: 0807007935 | 200 pages | PDF | 1.34 Mb
One father, 3 years, and thousands of rides

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Dreaming and Memory
Free Download Dreaming and Memory: Philosophical Issues
English | 2024 | ISBN: 3031682033 | 392 Pages | PDF EPUB (True) | 11 MB
This edited volume is the first systematic philosophical investigation of the complex and multifarious relationships between dreaming and memory. Featuring fifteen contributions by leading researchers, it explores a range of issues that arise when dreaming and memory are considered together. What does one remember when one remembers what one dreamt, and what is it for a memory of a dream to be accurate? What are the phenomenological, cognitive, and epistemic similarities and dissimilarities between dreaming and remembering? How does the self figure in dreams and memories? The book will serve as an indispensable resource both for philosophers interested in dreaming or memory and for their philosophically-minded colleagues in empirical disciplines and will provide an invaluable starting point for advanced students in need of a snapshot of the state of the art in philosophical research on dreaming and memory.

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Dreaming Techniques Working with Night Dreams, Daydreams, and Liminal Dreams (2024)
Free Download Serge Kahili King, "Dreaming Techniques: Working with Night Dreams, Daydreams, and Liminal Dreams"
English | 2020 | pages: 240 | ISBN: 1591433886 | EPUB | 1,4 mb
Harness the transformative power of night dreams, half-awake dreams, and daydreams for healing, manifestation, and insight

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Drawing Realistic Pets from Photographs
Free Download Lee Hammond, "Drawing Realistic Pets from Photographs"
English | 2005 | pages: 130 | ISBN: 158180640X | PDF | 5,2 mb
Draw gorgeous portraits of your favorite pets! Turn your candid snapshots into remarkable artwork that truly captures the personality of your cherished animals. In Drawing Realistic Pets from Photographs you'll find foolproof instruction that will have you creating impressive drawings in no time. Don't let a lack of natural artistic ability or drawing experience discourage you. Best-selling author and longtime art instructor Lee Hammond can teach everyone to draw. Her fail-proof grid method and simple penciling techniques have led thousands of beginners to undeniable drawing success. Twenty-nine step-by-step projects show you how surprisingly easy it is to render all your favorite animals, including cats, dogs, birds, rabbits, hamsters and more. You'll learn how to draw overall form and facial features accurately, plus the subtleties that make your pet unique. Capture every charming expression, every adorable pose in a work of art that you can proudly display and enjoy for years to come. With Drawing Realistic Pets from Photographs, it's easier than you think!

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  Author: creativelivenew1   |   11 November 2024   |   Comments icon: 0
Douglas XB–19 America's giant World War II intercontinental bomber (X–Planes)
Free Download Douglas XB-19: America's giant World War II intercontinental bomber (X-Planes) by William Wolf, Adam Tooby
English | October 26, 2021 | ISBN: 1472847199 | 80 pages | MOBI | 21 Mb
An authoritative, superbly illustrated history of the huge Douglas XB-19 intercontinental bomber, the biggest bomber the United States built in World War II.

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