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Fascinating Problems for Young Physicists Discovering Everyday Physics Phenomena and Solving Them

Fascinating Problems for Young Physicists Discovering Everyday Physics Phenomena and Solving Them
English | 2022 | ISBN: 1009160281 | 253 pages | PDF | 5.8 MB
Problem-solving is the cornerstone of all walks of scientific research. Fascinating Problems for Young Physicists attempts to clear the boundaries of seemingly abstract physical laws and their tangible effects through a step-by-step approach to physics in the world around us. It consists of 42 problems with detailed solutions, each describing a specific, interesting physical phenomenon. Each problem is further divided into questions designed to guide the reader through, encouraging engagement with and learning the physics behind the phenomenon. By solving the problems, the reader will be able to discover, for example, what the relation is between the mass of an animal and its expected lifetime, or what the efficiency limit is of wind turbines. Intended for first-year undergraduate students and interested high school students, this book develops inquiry-based scientific practice and enables students to acquire the necessary skills for applying the laws of physics to realistic situations.

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Exploring the Biotechnological Potential of C2 Alternative Substrates in Biocatalysis and Metabolic Engineering

Exploring the Biotechnological Potential of C2 Alternative Substrates in Biocatalysis and Metabolic Engineering
English | 2022 | ISBN: 168507555X, 978-1685075552 | 270 pages | True PDF | 11.35 MB
Metabolic engineering and biocatalysis aim to produce new value-added products from biological routes through careful and deliberate genetic engineering in different microbial chassis with suitable metabolic repertoire. Hitherto, the endeavor has largely been confined to the production of new products from glucose and a few other well characterized substrates. But, as the bioeconomy gains in importance and the world seeks to explore new sources of carbon as feedstocks, a possibility exists in developing alternative C2 compounds as feedstocks in contrast to the current reliance on C6 (glucose and fructose), C5 (xylose) and C3 (glycerol) substrates. Two potential C2 alternative substrates explored in this work are ethanol and ethylene glycol. Ethanol is a biofuel whose biotechnological potential has not been fully explored. In the first part of the book, the potential of using the NADH generated from a reconstructed ethanol utilization pathway to power a biotransformation reaction is explored in Escherichia coli. Experimental results indicate that ethanol utilization delivers higher biotransformation efficiency compared to state-of-the-art glucose dehydrogenase system, which confirmed theoretical predictions of relative efficiency of the two systems. Next, the book switches attention to ethylene glycol which could be derived as breakdown products of lignocellulosic waste or from plastic waste. Here, the proposal is to demonstrate the potential of an NADH generating ethylene glycol utilization pathway that terminates at glycolate to support biocatalytic reactions in E. coli. Subsequently, the two-step ethylene glycol utilization pathway would be extended to malate and 2-phosphoglycerate to help another biotechnology workhorse, Bacillus subtilis, to grow on ethylene glycol as the sole carbon source. Different connection points to central carbon metabolism would provide a natural experiment to decipher the relative efficiencies of activating tricarboxylic acid cycle and glycolysis in supporting cell growth, and illuminate insights into the relative efficiency and evolutionary importance of different branches of metabolism in B. subtilis. Finally, ethylene glycol utilization would be combined with product formation to help B. subtilis to synthesize green fluorescent protein using flux from the C2 alternative substrate. This system would provide a platform for examining the efficacy of different ethylene glycol utilization pathways and entry points in central carbon metabolism in synthesizing amino acids and proteins. Overall, this book hopes to explore the biotechnological potential of two alternative C2 substrates (ethanol and ethylene glycol) in biocatalysis and metabolic engineering from the substrate utilization perspective.

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Evil Roman Emperors The Shocking History of Ancient Rome's Most Wicked Rulers from Caligula to Nero and More (True PDF)

Evil Roman Emperors The Shocking History of Ancient Rome's Most Wicked Rulers from Caligula to Nero and More (True PDF)
English | 2021 | ISBN: 1633886905 | 237 pages | True PDF | 76.32 MB
Nero fiddled while Rome burned. As catchy as that aphorism is, it's sadly untrue, even if it has a nice ring to it. The one thing Nero is well-known for is the one thing he actually didn't do. But fear not, the truth of his life, his rule and what he did with unrestrained power, is plenty weird, salacious and horrifying.

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Essentials of Biostatistics for Public Health, 4th Edition

Essentials of Biostatistics for Public Health, 4th Edition
English | 2022 | ISBN: 1284231976 | 405 pages | True EPUB | 288.44 MB
Essentials of Biostatistics in Public Health, Fourth Edition provides a fundamental and engaging background for students learning to apply and appropriately interpret biostatistics applications in the field of public health. Many examples are drawn directly from the author's remarkable clinical experiences with the renowned Framingham Heart Study, making this text practical, interesting, and accessible for those with little mathematical background. The examples are real, relevant, and manageable in size so that students can easily focus on applications rather than become overwhelmed by computations. The Fourth Edition has been thoroughly updated, and now offers a new chapter on career opportunities and new case studies in each chapter focused on COVID-19. This edition will also include free access to JMP Student Edition Software, which is a streamlined version of SAS' statistical discovery software and is well-suited to for introductory or intermediate statistics courses.

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Essential Sleep Medicine and Surgery

Essential Sleep Medicine and Surgery
English | 2022 | ISBN: 1685072208, 978-1685072209 | 702 pages | True PDF | 13.82 MB
"This textbook presents a succinct yet comprehensive overview of the current essential topics in sleep medicine. Each chapter, written by experts in the many fields that make up sleep medicine, provides a unique, multidisciplinary perspective on the diagnosis and management of sleep disorders. Information is presented in outline format to optimize the learning experience with multiple choice questions to consolidate learning and practice guidelines to further one's grasp of the topics while presenting the opportunity for efficient reference. Finally, this textbook's outline format, clear and concise language, and rich set of practice guidelines make it a trusted resource for nonmedical professionals hoping to learn more about sleep disorders and their treatments"--

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