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A Pharmacology Primer Techniques for More Effective and Strategic Drug Discovery, 6th Edition

English | 2022 | ISBN: 0323992897 | 504 pages | True PDF EPUB | 238.39 MB
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets.

Pharmacology of Drug Stereoisomers
English | 2022 | ISBN: 9811923191 | 218 Pages | PDF EPUB (True) | 16 MB
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.

Encyclopedia of Molecular Pharmacology by Stefan Offermanns
English | PDF | 2008 | 1514 Pages | ISBN : 3540389164 | 59.4 MB
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

DR NAZMUL ALAM, "VISUAL MNEMONICS PHARMACOLOGY 2nd EDITION"
English | 2019 | pages: 125 | ISBN: 1697744990 | PDF | 11,1 mb
This book is about Pharmacology medical mnemonics with unique diagrammatic representation. It will cover the important medical topic in a very concise and beneficiary way to the medical students. The mnemonics will not will help you to memorize but also help you to picturise about the content. Most important feature of this book is that all the pictures are related to the mnemonic. This new edition contains 200+ Visual mnemonics and 500+ High-Yield Drug of Choice.

The Nature of Drugs Vol. 1 History, Pharmacology, and Social Impact [Audiobook]

English | ASIN: B0B8M8G5FX | 2022 | 10 hours and 57 minutes | MP3 | M4B | 301 MB
The Nature of Drugs presents Sasha Shulgin's popular San Francisco State University course on what drugs are, how they work, how they are processed by the body, and how they affect our society. The course also delves into social issues and reactions involving drugs, and discussions of governmental attempts at controlling them and features Sasha's engaging lecture style peppered with illuminating anecdotes and amusing asides.
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Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models By C.P. Coyne(auth.)
2006 | 933 Pages | ISBN: 0813817536 | PDF | 8 MB
Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models is the first evidence-based reference text devoted exclusively to the subject of applying pharmaceutical and biopharmaceutical agents as diagnostic probes in clinical medicine and investigative research.This unique and groundbreaking book is a versatile guide for clinicians and researchers interested in using pharmacologic agents to: Diagnose disease Assess physiological processes Identify the appropriateness of a therapeutic agent Determine appropriate dosing for therapeutic use.Extensively referenced and organized by major body systems, individual topics are listed in an evidence-based format according to specific disease processes or physiological processes of interest. Each entry also includes information on the mechanism of action, administration, and diagnostic interpretation.Descriptions have been provided for the application of diagnostic pharmaceuticals to assess a wide spectrum of diseases and physiological processes relevant to the fields of veterinary and human medicine. Comparative Diagnostic Pharmacology is useful not merely for pharmaceutical-oriented research investigations, but it will also prove invaluable for the monitoring and evaluation of physiological responses and disease processes in animal models.Content: Chapter 1 Cardiovascular System (pages 5-60): Chapter 2 Central Nervous System (pages 61-127): Chapter 3 Endocrine System (pages 129-177): Chapter 4 Gastrointestinal System (pages 179-220): Chapter 5 Hematopoietic System (pages 221-266): Chapter 6 Hepatic System (pages 267-335): Chapter 7 Integumentary System (pages 337-339): Chapter 8 Musculoskeletal System (pages 341-349): Chapter 9 Reproductive System (pages 351-354): Chapter 10 Renal and Urinary Systems (pages 355-373): Chapter 11 Respiratory System (pages 375-403): Chapter 12 Cancer/Neoplastic Disease (pages 407-424): Chapter 13 Genetics and Nucleic Acids (pages 425-438): Chapter 14 Inflammation, Infection, and Sepsis (pages 439-453): Chapter 15 Metabolism, Electrolytes, and Hypoxia (pages 455-470): Chapter 16 Fluorescent and Pigment Dye Reagents (pages 473-516): Chapter 17 Magnetic Resonance Imaging (MRI) (pages 517-567): Chapter 18 Nuclear Planar Scintigraphy (pages 569-675): Chapter 19 Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) (pages 677-729): Chapter 20 Radiographic Image?Enhancing Agents (pages 731-764): Chapter 21 Ultrasonography (pages 765-808): Chapter 22 Biological and Synthetic Delivery Modalities (pages 811-905):

Introduction to Basics of Pharmacology and Toxicology Volume 3

A Pharmacology Primer Techniques for More Effective and Strategic Drug Discovery, 6th Edition

Pharmacology of Drug Stereoisomers

Encyclopedia of Molecular Pharmacology

VISUAL MNEMONICS PHARMACOLOGY 2nd EDITION

Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences

The Nature of Drugs Vol. 1 History, Pharmacology, and Social Impact [Audiobook]

Comparative Diagnostic Pharmacology Clinical and Research Applications in Living-System Models

Udemy - Hepatitis C Pharmacology

Learn Gastrointestinal Pharmacology And Pharmacotherapy