What you'll learn Definition of biocompatibility and biomaterials Study of biocompatibility from the point of view of toxicity, allergenicity, effect on genes and blood, carcinogenicity and biodegradability Introduction of biocompatibility standards The interaction of cells with biomaterials Physicochemical properties of biomaterials and their biocompatibility Compatibility blood and the factors affecting it The process of wound healing in the presence of natural and artificial biomaterials Requirements System requirements: PC, laptop or mobile device (with Udemy app) and broadband connectivity. Course requirements: There are no pre-requisite or other course requirements. Description Biocompatibility means the adaptation of biomaterial to biological conditions and the absence of harmful toxic effects. Scaffold biocompatibility means the ability to regenerate tissue with the body without producing harmful systemic and local responses in the host. Interaction between body and biomaterials will have a significant effect on biomaterial Function. There is a great deal of interaction between the body and the biomaterial. There are three basic characteristics of this definition: first, that biomaterial must work, second, that the best response from the body's tissues to biomaterial is necessary, and third, that biocompatibility must always be defined for a specific application. Biomaterial biocompatibility is its ability to create optimal performance in the host with an acceptable surface of connective tissue binding without creating adverse local systemic responses. The biocompatibility of scaffolding is defined as the ability of the structure to support appropriate cellular activities to optimize tissue regeneration without creating adverse systemic and local responses in the host.This course provides an overview of:- Definition of biocompatibility and biomaterials- Study of biocompatibility from the point of view of toxicology, allergenicity, effect on genes and blood, carcinogenicity and biodegradability- Introduction of biocompatibility standards- The interaction of cells with biomaterials- Physicochemical properties of biomaterials and their biocompatibility- Compatibility blood and the factors affecting it- The process of wound healing in the presence of natural and artificial biomaterialsThis course can be useful for students of tissue engineering, polymer and medical engineering and interested in this field. Overview Section 1: Definition of biocompatibility and biomaterials Lecture 1 Biocompatibility definition Lecture 2 Biocompatibility control factors Lecture 3 Chemical biocompatibility Lecture 4 Mechanical biocompatibility Lecture 5 Structural biocompatibility Lecture 6 Electrical Biocompatibility Section 2: Study of biocompatibility from the point of view of toxicity allergenicity, .. Lecture 7 Medical devices contact with the body Lecture 8 Cellular toxicity Lecture 9 External tests used to assess cell toxicity Lecture 10 Direct contact test Lecture 11 Extract test Lecture 12 Agar diffusion test Lecture 13 Cellular adhesion Lecture 14 Cell morphology Lecture 15 Sensitization Assays Lecture 16 Irritation Tests Lecture 17 Acute systemic toxicity and chronic toxicity Lecture 18 Genotoxicity Lecture 19 Implantation Tests Lecture 20 Hemocompatibility Lecture 21 Carcinogenesis Bioassay Section 3: Introduction of biocompatibility standards Lecture 22 Biocompatibility standards Section 4: The interaction of cells with biomaterials Lecture 23 Protein-biomaterial interaction (Protein properties Lecture 24 Biomaterial surface properties Lecture 25 Cell-biomaterial interaction Lecture 26 Extracellular matrix and its interaction with biomaterials Lecture 27 Tissue-biomaterial interaction Section 5: Physicochemical properties of biomaterials and their biocompatibility Lecture 28 Physicochemical properties of biomaterials and their biocompatibility Lecture 29 The relationship between biocompatibility and the immune system Lecture 30 Immune response control factors Section 6: Compatibility blood and the factors affecting it Lecture 31 Different types in the interaction of platelets with the surface Lecture 32 Factors affecting blood compatibility Section 7: The process of wound healing in the presence of natural and artificial biomateri Lecture 33 The wound healing process Lecture 34 Wound repair in the presence of biomaterials Lecture 35 Natural and artificial blood vessels Section 8: lesson's text Lecture 36 lesson's text This course can be useful for students of tissue engineering, polymer and medical engineering and anyone who is interested.
