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 Galectins and Disease Implications for Targeted Therapeutics By Anatole A. Klyosov and Peter G. Traber (Eds.) 2012 | 425 Pages | ISBN: 0841228809 | PDF | 12 MB Content: CONTENTS ; PREFACE ; OVERVIEW ; 1. GALECTINS IN DISEASE AND POTENTIAL THERAPEUTIC APPROACHES ; ANATOLE A. KLYOSOV AND PETER G. TRABER ; GALECTIN AND GALECTIN INHIBITORS: STRUCTURAL ASPECTS ; 2. LOW-MOLECULAR WEIGHT INHIBITORS OF GALECTINS ; HAKON LEFFLER AND ULF J. NILSSON ; 3. FROM CARBOHYDRATE TO PEPTIDOMIMETIC INHIBITORS OF GALECTINS ; KEVIN H. MAYO ; GALECTIN EXTRA- AND INTRA-CELLULAR FUNCTIONS AND ; THEIR THERAPEUTIC IMPLICATIONS ; 4. INTRACELLULAR GALECTINS: PLATFORMS FOR ASSEMBLY OF MACROMOLECULAR ; COMPLEXES ; JOHN L. WANG, KEVIN C. HAUDEK, PATRICIA G. VOSS, RONALD J. PATTERSON, AND ; ERIC J. ARNOYS ; 5. GALECTINS AS NOVEL REGULATORS OF PLATELET SIGNALING AND FUNCTION: ; THERAPEUTIC IMPLICATIONS ; GABRIEL A. RABINOVICH AND MIRTA SCHATTNER ; 6. GALECTIN-1 CROSS-LINKING OF GM1 GANGLIOSIDE IN AUTOIMMUNE ; SUPPRESSION ; ROBERT W. LEDEEN, GUSHENG WU, DAVID BLEICH, ZI-HUA LU, AND HANS-JOACHIM GABIUS ; 7. HOW TO BUILD "LEAN AND MEAN" ANTI-TUMOR T CELLS: A STRATEGIC VIEW INTO ; THE ANTI-CARBOHYDRATE ACTION OF FLUORINATED GLUCOSAMINE ANALOGS ; CHARLES J. DIMITROFF ; 8. POST-TRANSLATIONAL MODIFICATION OF GALECTIN-3 AND ITS ROLE IN BIOLOGICAL ; FUNCTION ; JAMES C. BYRD, NACHMAN MAZUREK, AND ROBERT S. BRESALIER ; GALECTIN MECHANISMS AND THERAPEUTIC APPROACHES IN CANCER ; 9. THE ROLE OF GALECTIN-3 IN MALIGNANT MELANOMA ; GORDANA RADOSAVLJEVIC, IVAN JOVANOVIC, JELENA PANTIC, NADA PEJNOVIC, ; NEBOJSA ARSENIJEVIC, DANIEL K. HSU, AND MIODRAG L. LUKIC ; 10. GALECTINS AS NOVEL TARGETS FOR THE TREATMENT OF MALIGNANT GLIOMAS ; HERWIG M. STRIK AND MATTHIAS OCKER ; 11. DYNAMIC TUNING OF GALECTINS AND THEIR BINDING SITES DURING MAMMARY ; TUMOR PROGRESSION AND METASTASIS ; JOANA T. DE OLIVEIRA AND FATIMA GARTNER ; 12. GALECTIN-3C: HUMAN LECTIN FOR TREATMENT OF CANCER ; GARY A. JARVIS, LEONARDO MIRANDOLA, YU YUEFEI, EVERARDO COBOS, ; MAURIZIO CHIRIVA-INTERNATI, AND CONSTANCE M. JOHN ; 13. ANGIOSTATIC CANCER THERAPY BY TARGETING GALECTINS IN THE TUMOR ; VASCULATURE ; IRIS A. SCHULKENS, ARJAN W. GRIFFIOEN, AND VICTOR L. THIJSSEN ; 14. GALECTINS AND PATHOLOGIES: ROLE OF GALECTIN-3 IN THE COMMUNICATION ; BETWEEN LEUKEMIA CELLS AND THE MICROENVIRONMENT ; NORA HEISTERKAMP, FEI FEI, AND JOHN GROFFEN ; 15. TRANSLATIONAL RATIONAL FOR THE CLINICAL DEVELOPMENT OF OTX-008: A NOVEL ; DRUG THAT INHIBITS GALECTIN-1 EXPRESSION IN HUMAN CANCER MODELS ; ERIC RAYMOND, LUCILE ASTRORGUE-XERRI, MARIA SEROVA, MARIA EUGENIA RIVEIRO, AND ; SANDRINE FAIVRE ; 16. IMPROVING THE CLINICAL EFFICACY OF CANCER VACCINES BY TARGETING IMMUNE ; SUPPRESSION IN HUMAN TUMORS ; NATHALIE DEMOTTE, ARISTOTELIS ANTONOPOULOS, JEAN-FRANCOIS BAURAIN, GREGOIRE WIEERS, ; NICOLAS VAN BAREN, AND PIERRE VAN DER BRUGGEN ; 17. TARGETING GALECTIN-3 UNVEILS THE COMPLEXITY OF MULTIPLE MYELOMA: A ; SWEET CONTEXT ; LEONARDO MIRANDOLA, YUEFEI YU, CONSTANCE M. JOHN, MARJORIE JENKINS, ; EVERARDO COBOS, AND MAURIZIO CHIRIVA-INTERNATI ; 18. GALECTINS IN THE BLOOD CIRCULATION: POTENTIAL THERAPEUTIC TARGETS OF ; CANCER METASTASIS ; CARRIE A. DUCKWORTH AND LU-GANG YU ; GALECTIN MECHANISMS AND THERAPEUTIC APPROACHES IN ; INFLAMMATION AND FIBROSIS ; 19. A THERAPEUTIC ROLE FOR GALECTINS IN ACUTE INFLAMMATION? ; DIANNE COOPER ; 20. GALECTINS IN IMMUNE AND INFLAMMATORY DISEASES: INSIGHTS FROM ; EXPERIMENTS WITH GALECTIN DEFICIENT MICE ; DANIEL K. HSU, RI-YAO YANG, AGNES FERMIN, AND FU-TONG LIU ; 21. AUTOIMMUNE DISORDERS IN GALECTIN-3 DEFICIENT MICE ; VLADISLAV VOLAREVIC AND MIODRAG L. LUKIC ; 22. GALECTIN-3: A CENTRAL REGULATOR OF CHRONIC INFLAMMATION AND TISSUE ; FIBROSIS ; NEIL C. HENDERSON, ALISON C. MACKINNON, CLAIRE ROONEY, AND TARIQ SETHI ; 23. THE ROLE OF GALECTIN-3 IN STELLATE CELL ACTIVATION AND LIVER FIBROSIS ; JOY X. JIANG, XIANGLING CHEN, HIROO FUKADA, DAN K. HSU, FU-TONG LIU, AND ; NATALIE J. TOROK ; 24. GALECTIN-3 MEDIATED CARDIOVASCULAR FIBROGENESIS: AN IMPORTANT CAUSE OF ; HEART FAILURE AND CARDIOVASCULAR MORTALITY ; WOUTER C. MEIJERS AND RUDOLF A. DE BOER ; 25. MUCINS AND GALECTIN-3 IN OCULAR SURFACE HEALTH AND DISEASE ; JEROME MAURIS AND PABLO ARGUESO ; 26. ROLE OF GALECTINS IN WOUND HEALING ; NOORJAHAN PANJWANI, PH.D. ; EDITORS' BIOGRAPHIES ; INDEXES ; AUTHOR INDEX ; SUBJECT INDEX
 Full Upper Body Home Workout in 4 mins - GET RID OF FLABBY FAT in Arms and Slim Back and Waist in 7 Days by Minimalistic Workout English | 2022 | ISBN: N/A | ASIN: B09S336S27 | 45 pages | EPUB | 2.55 Mb Full Upper Body Home Workout in 4 mins - GET RID OF FLABBY FAT in Arms and Slim Back and Waist in 7 Days
 Maria Eugenia Ibarrarán, "From Human to Post Human Security in Latin America: Examples and Reflections from Across the Region" English | ISBN: 1800712537 | 2021 | 180 pages | EPUB | 1531 KB Current political discourse emphasizes the globalized nature of security threats, and focusing on Latin America, this book identifies local complexities of Human Security.  Elizabeth David, "French Provincial Cooking" English | ISBN: 1904943713 | 2007 | 528 pages | EPUB | 2 MB Elizabeth David's books belong in the libraries of everyone who loves to read and prepare food and this one is generally regarded as her best; her passion and knowledge comes through on every page. She was one of the foremost writers on food in the latter half of the 20th century and this book has her most celebrated writing. "French Provincial Cooking" should be approached and read as a series of short stories, as well written and evocative as the best literature.
 Ivan Varzinczak, "Foundations of Information and Knowledge Systems: 12th International Symposium, FoIKS 2022, Helsinki, Finland, June 20-2" English | ISBN: 3031113209 | 2022 | 255 pages | PDF | 4 MB This book constitutes the refereed proceedings of the 12th International Symposium on Foundations of Information and Knowledge Systems, FoIKS 2022, held in Helsinki, Finland, in June 2022.  Forms of Dwelling : 20 years of Taskscapes in archaeology by Ulla Rajala and Philip Mills English | 2017 | ISBN: 1785703773 | 290 Pages | True PDF | 4.22 MB  Fodor's Essential Turkey (Full-color Travel Guide), 2nd Edition by Fodor's Travel Guides English | July 12th, 2022 | ISBN: 1640975047 | 448 pages | True EPUB | 41.76 MB Whether you want to visit the Grand Bazaar in Istanbul, cruise along the Turquoise Coast, or go hot-air ballooning in Cappadocia, the local Fodor's travel experts in Turkey are here to help! Fodor's Essential Turkey guidebook is packed with maps, carefully curated recommendations, and everything else you need to simplify your trip-planning process and make the most of your time. This new edition has been fully-redesigned with an easy-to-read layout, fresh information, and beautiful color photos.  William F. Buckley Jr., "Flying High: Remembering Barry Goldwater" English | 2010 | ISBN: 046501805X, 0465008364 | EPUB | pages: 224 | 0.2 mb If any two people can be called indispensable in launching the conservative movement in American politics, they are William F. Buckley Jr. and Barry Goldwater. Buckley's National Review was at the center of conservative political analysis from the mid-fifties onward. But the policy intellectuals knew that to actually change the way the country was run, they needed a presidential candidate, and the man they turned to was Arizona Senator Barry Goldwater. Goldwater was in many ways the perfect choice: self-reliant, unpretentious, unshakably honest and dashingly handsome, with a devoted following that grew throughout the fifties and early sixties. He possessed deep integrity and a sense of decency that made him a natural spokesman for conservative ideals. But his flaws were a product of his virtues. He wouldn't't bend his opinions to make himself more popular, he insisted on using his own inexperienced advisors to run his presidential campaign, and in the end he electrified a large portion of the electorate but lost the great majority. Flying High is Buckley's partly fictional tribute to the man who was in many ways his alter ego in the conservative movement. It is the story of two men who looked as if they were on the losing side of political events, but were kept aloft by the conviction that in fact they were making history.
 First Battle of Bull Run: A History from Beginning to End (American Civil War) by Hourly History English | 2022 | ISBN: N/A | ASIN: B0B4K32Y18 | 50 pages | EPUB | 0.24 Mb Discover the remarkable history of the First Battle of Bull Run...
 Mark Hudson, "Fire Management in the American West: Forest Politics and the Rise of Megafires" English | 2011 | ISBN: 1607320886 | EPUB | pages: 256 | 1.1 mb Most journalists and academics attribute the rise of wildfires in the western United States to the USDA Forest Service's successful fire-elimination policies of the twentieth century. However, in Fire Management in the American West, Mark Hudson argues that although a century of suppression did indeed increase the hazard of wildfire, the responsibility does not lie with the USFS alone. The roots are found in the Forest Service's relationships with other, more powerful elements of society-the timber industry in particular. |
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