
Tuning Autophagy-Inducing Activity and Toxicity for Lanthanide Nanocrystals by Yunjiao Zhang
English | PDF,EPUB | 2022 | 169 Pages | ISBN : 9811681651 | 39.1 MB
This thesis presents a simple, yet highly effective surface engineering solution that uses non-covalent binding peptides to control the autophagy-inducing activity of nanomaterials and nanodevices. The author presents RE-1, a short synthetic peptide that sequence-specifically binds to lanthanide (LN) oxide and upconversion nanocrystals with high affinity, which was discovered using an innovative phage display approach.
RE-1 effectively inhibits the autophagy-inducing activity and toxicity of these nanocrystals by forming a stable coating layer on the surface of the nanoparticles, and by reducing their sedimentation and cell interaction. RE- 1 and its variants provide a versatile tool for tuning cell interactions in order to achieve the desired level of autophagic response and are useful for the various diagnostic and therapeutic applications of LN-based nanomaterials and nanodevices.
Buy Premium From My Links To Get Resumable Support,Max Speed & Support Me
https://hot4share.com/o5h6an88qrcz/pcv72.T.A.A.a.T.f.L.N.rar.html

https://rapidgator.net/file/8116e235ebe9efceca62231e6c72638b/pcv72.T.A.A.a.T.f.L.N.rar.html

https://uploadgig.com/file/download/30367da1Af7e8d44/pcv72.T.A.A.a.T.f.L.N.rar

https://nitro.download/view/98B2BCE6A25A53B/pcv72.T.A.A.a.T.f.L.N.rar